Enhancement of S-Adenosylmethionine-Dependent Methylation by Integrating Methanol Metabolism with 5-Methyl-Tetrahydrofolate Formation in Escherichia coli
نویسندگان
چکیده
منابع مشابه
Escherichia coli by Methanol
Stringent strains of microorganisms stop net ribonucleic acid (RNA) synthesis when deprived of their essential amino acids (18). The means by which the synchrony between RNA and protein biosynthesis is achieved has been the subject of research since the discovery of the relaxed mutant (2). This strain is genotypically capable of net RNA synthesis in the absence of net protein production. It was...
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Addition of methionine to the growth medium of Escherichia coli K-12 leads to a reduction in the specific activity of S-adenosylmethionine (SAM) synthetase. Thus the enzyme appears to be repressible rather than inducible. Mutant strains (probably metJ(-)) are constitutive for SAM synthetase as well as for the methionine biosynthetic enzymes, suggesting that the regulatory systems for these enzy...
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ژورنال
عنوان ژورنال: Catalysts
سال: 2020
ISSN: 2073-4344
DOI: 10.3390/catal10091001